ToxBank Public Forum Agenda

ToxBank Public Forum

Advances toward Replacement of Animal Testing

26 – 27 October 2015,
Wellcome Collection / London, United Kingdom


Day 1, 26th October 2015

Research progress supporting industrial application and regulatory acceptance

Chair: Barry Hardy

Time Topic Speakers
12:00 Buffet Lunch: Arrival & Registration !
13:00 Chair's Introduction •   Barry Hardy, Douglas Connect



Case Studies from the SEURAT-1* projects  
•    HeMiBio: A hepatic microfluidic Bioreactor
•    13:25 Platform for Chemical Safety Assessment
•    13:45 DETECTIVE
•    Catherine Verfailie, University of Leuven
•    Bob van de Water, Leiden University
•    Jos Kleinjans, University of Maastricht
14:05 Defining adverse outcome pathways from omics-driven bioinformatics and modeling approaches •    Roland Grafström / Pekka Konnen, Karolinska Institutet
14:25 •    A Path to Validation – SEURAT-1 case studies and the role of ECVAM •    Elisabet Berggren, EU Joint Research Centre
•    Industrial application of alternative testing methods for risk assessment •    Andrew White, Unilever
15:05 Key learning and advances obtained from alternatives programs on the Translation of new technologies in validated safety testing methods to industrial application and regulatory acceptance:  
•   An ethical perspective
•   Development of new toxicity assays
•   Emily McIvor, Humane Society
•  J Malcolm Wilkinson, Kirkstall Ltd
Coffee break
16:00 The ToxBank infrastructure project to support the replacement for repeated dose toxicity •  Glenn Myatt, Leadscope
16:20 A ToxBank Integrated Data Analysis of SEURAT-1 Reference Compounds •  Barry Hardy, Douglas Connect
16:40 Question & Answer forum  
17:30 End Session

*Safety Evaluation Ultimately Replacing Animal Testing (→ SEURAT)

Day 2, 27th October 2015

Application of Pluripotent Stem Cells for safety testing and disease studies

Chair: Glyn Stacey

Time Topic Speakers
09:00 Arrival and registration !
09:15 Welcome Coffee, Tea
09:30 Chair's Introduction •    Glyn Stacey, National Institute for Biological Standards and Control
09:35 StemBANCC: iPSC Models for Drug Discovery & Safety Assessment •    Jim Ross, University of Edinburgh - MRC Centre for Regenerative Medicine
10:10 European Commission funding in stem cell research and the need for ethical research governance •    Joana Namorado, European Commission
10:45 Coffee break !
11:15 Scientific and ethical qualification of pluripotent stem cells for European research - hPSCreg •    Andreas Kurtz, Charité
12:00 Lunch – Poster session  
13:00 EBiSC: Access to HIPSc Line Acquisition via the EBiSC •    Paul de Sousa, Roslin Cells
End Session

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